For most autistics in North America, one of the biggest thorns in their side is Autism Speaks. They are scumbags, through and through, as evidenced by this alarmist windbagging from Suzanne Wright, founder of Autism Speaks and world's biggest self-pitying soccer mom.
It's a tragedy, because they are probably the biggest autism-related charity in the US (if not the world), and as a result they have access to immense volumes of finances, "mindshare"/name recognition, etc. They could have been a tool used for incredible good: to provide support staff in schools, therapy centers, even just professional paper-pushers to help parents and autistic adults navigate a large and confusing bureaucracy.
But as Queen Whingey Soccer Mom made clear, that's not what she's about. Since in the middle of an Internet shitstorm is as good a time to post as anything, I will let those links (which are worth reading) speak for themselves, and provide the link-phobic with an alternative charity: the Autistic Self-Advocacy Network.